Two different microtubule-based motor activities with opposite polarities in kinetochores.

Citation:

Hyman AA, Mitchison TJ. Two different microtubule-based motor activities with opposite polarities in kinetochores. Nature. 1991;351 (6323) :206-11.

Date Published:

1991 May 16

Abstract:

The movement of microtubules on the kinetochores of isolated chromosomes has been examined by video microscopy. Two different microtubule-based motors on the kinetochore were identified, which have opposite directions of movement. The activities of these two motors can be regulated by factors that can influence phosphorylation.